A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. In the placebo group, the retinopathy worsened; whereas, in the Pycnogenol-treated group, there was no deterioration. (adsbygoogle = window.adsbygoogle || []).push({}); Heart Palpitations at Night: Common Causes and How to Treat, Essential Oils for Cough, Cold and Congestion, Sudden High Blood Pressure: Causes, Symptoms and Prevention Tips, Sore Throat on One Side: 7 Causes and Treatments, Natural Remedies for the Burning Sensation in Your Stomach After Eating, Hibiscus Tea: Health Benefits, Nutrition, Side Effects, and Recipes, Vegetable Oil Substitutes: 5 Healthy Alternatives for Baking, Frying, and More, How to Treat Nausea After Eating Eggs or Chicken, Diarrhea after Eating: Causes and Natural Treatments, Top 11 Homeopathic Remedies for High Blood Pressure, Heavy Breathing: Common Causes and Treatments, Pineapple Juice for Cough: Effective Homemade Cough Remedies, Pain in the Left Temple of the Head: 10 Causes and Treatments. Sort By. These benefits appeared to persist for some time even after stopping supplementation [72]. Researchers suggest it may boost sustained attention, memory, executive functions, mood, and reduce oxidative stress [19]. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. Folic Acid Benefits, Deficiency, Foods, Side Effects, More - Dr. Axe Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. 8 Proven Benefits of Pine Bark Extract - Healthy Focus , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. This study adds to a body of research showing the benefits of Pycnogenol . However, with the addition of twice-daily Pycnogenol, normal erection increased to 80%, which further increased to 92.5% during the third month on thrice-daily Pycnogenol. Low-dose Pycnogenol (30 mg/day) may reduce pain in pregnant women, particularly hip, joint, lower back, groin, and calf cramps in the third trimester [71]. Pycnogenol is the US trademarked name for an antioxidant made from Mediterranean tree bark. She is a strong advocate of integrating scientific knowledge and holistic medicine. Pycnogenol is a compound of natural chemicals. Once youre sure that you dont have any negative reactions, you may be able to increase your dosage according to the label. Our website services, content, and products are for informational purposes only. Pycnogenol (up to 200 mg/day) may improve asthma and reduce inflammatory asthma markers in the blood, leukotrienes, after 4 weeks, according to a randomized placebo-controlled trial of 26 asthma patients [14]. It may cause side effects such as: Dizziness. Luckily, the Native Americans told them about a tea prepared from the bark of a certain tree, which miraculously led to complete recovery. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. SelfDecode does not treat, diagnose or cure any conditions, Pycnogenol: French maritime pine bark extract As a skin powder, however, you can use it safely for up to six weeks. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. 6 Vinpocetine Benefits + How It Works & Side Effects Although these may still be high quality, the active compounds are more likely to vary. Learn more about how to get even skin tone. Pycnogenol seems to help with asthma and allergies. Note that the numbers in parentheses (1, 2, etc.) This study adds to a body of research showing the benefits of Pycnogenol for improving circulation and blood flow, strengthening the vascular system and managing cholesterol. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. Pycnogenol is a standardized supplement formula guaranteed to contain at least 65-75% proanthocyanidins, the active . There were 88 in the control group and 81 in the Pycnogenol group. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. Pycnogenol may have benefits for heart and artery health. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. Ana spent years working with patients who suffer from various mental health issues and chronic health problems. Posted on Thursday, August 14, 2014 The majority of this article is information obtained from the book "All About DIM" by Michael A. Zeligs, MD and A. Scott Connelly, MD. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. Pycnogenol completely normalized function. 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. Based on another study of 6 trained and 7 untrained people, an antioxidant combination product containing Pycnogenol (Lactaway) may increase endurance. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for . Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. The goal of one study was to evaluate whether or not Pycnogenol could prevent edema (fluid build-up) during long-haul flights in healthy people. A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. The researchers of the study propose that pycnogenol may reduce pain and cramps during retraining and rehabilitation in people with blood vessel problems [11]. A trial of 86 people with eye damage from diabetes found that antioxidant therapy (including pycnogenol, vitamin E, and Coenzyme Q10) may improve eye health and reduce reactive oxygen species levels [35]. Pycnogenol: Properties Clinical research suggests that Pycnogenol is possibly effective for improving athletic performance. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. Diabetes-associated small blood vessel changes is the leading cause of diabetic ulcers. Gotu Kola: Health Benefits, Side Effects, Uses, and More - WebMD A randomized clinical trial of 30 people found that Pycnogenol (150 mg/day) may help heal vein ulcers from surgery and reduce swelling after 3 months of treatment [25]. Some health benefits of Pycnogenol include:. In the control group, there were five thrombotic events; whereas the Pycnogenol-treated subjects only experienced nonthrombotic, local flare-ups. What gives pine bark extract its notoriety as a powerful ingredient and super antioxidant is that its loaded with oligomeric proanthocyanidin compounds, OPCs for short. The first studied group included 66 healthy subjects in whom the number of muscle cramps was recorded two weeks before entering the study and during the fourth and fifth week. Diarrhea. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. Chanca Piedra: Benefits, Dosage, Side Effects, and More - Healthline For people who have symptoms that are more severe, traditional medicine is probably more effective. For mild high blood pressure: 200 milligrams daily. Twenty-one patients were given Pycnogenol at 150 mg daily and 18 patients received no treatment for a period of eight weeks. Pine bark extract comes from the inner bark of the Pinus pinaster tree, most commonly found in Europe. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. A trial of 132 people found that Pycnogenol (150 mg/day) may improve risk factors of metabolic syndrome including lowering triglyceride levels, blood pressure, and fasting glucose, decreasing waist circumference, and increasing HDL cholesterol levels [29]. Certain studies used combination products, so its unknown what the contribution of Pycnogenol itself was. According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. 5) Vein Diseases and Swelling. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. Studies on human subjects have reported few side effects - even . Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. Too much pressure signals that your heart might be working too hard. . Pycnogenol can help control blood pressure, which helps improve overall heart health. Its true. High levels of both of these are considered risk factors for heart disease. 2. Organika Pycnogenol 50mg 50 Tablets . Neuroprotective effect of Pycnogenol® following traumatic brain injury. The list goes on a bit further, as the OPCs in thisextract may inhibit lipid peroxidation, platelet aggregation, capillary permeability and fragility, and to affect enzyme systems, which basically means it may be a natural treatment for many serious health conditions, such as stroke and heart disease. Healthline Media does not provide medical advice, diagnosis, or treatment. Forty-seven Japanese men with mild erectile dysfunction were given supplementation L-arginine and French maritime pine bark extract over a period of time. Side effects. 6 Amazing Benefits of Nattokinase | Organic Facts Pine bark distill has been studied regarding its relationship to exercise performance, oxidative stress and excitement to torso that has been imposed by exercise. Add to Cart. Moreover, Pycnogenol group either reduced or discontinued the use of asthma drugs. Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. (2013). There is limited evidence that it could be used in treating Attention Deficit Hyperactivity Disorder (ADHD). It also reduced the size of scars. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. All of our content is written by scientists and people with a strong science background. But, as you know, going for the natural approach can make a huge difference in overall health. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. Pycnogenol French maritime pine bark extract's 4 basic properties. Seems like it must be pretty amazing, but lets look closer. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. What Is Pycnogenol, and What's It Used For? - Wonder Labs Researchers suggest that it may have stronger benefits than elastic compression stockings. Studies have found that supplementing with pycnogenol effectively strengthens the blood vessels, stabilizing blood pressure. All rights reserved. A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). Pycnogenol Health benefits, dosage, safety, side-effects, and more Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. The same ingredient can be found in grapeseed oil, the skin of peanuts and witch hazel bark. Take Helpful Supplements. The authors attributed the negative results to the short duration of treatment and the low dosages of drug or Pycnogenol. Here are 12 benefits of ginkgo biloba. A trial of children with ADHD found that Pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing DNA damage. Pycnogenol Review - Worlds Best Anti-Aging Supplement? According to the lab results of 10 volunteers, a higher Pycnogenol dose (300 mg) may impact these enzymes after just 30 minutes [52]. Blazs G, et al. Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. chronic anal fissure may take more than 6 weeks to heal. (8). Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. However, it can also be used topically. This includes supporting healthy blood circulation, acting as a natural anti-inflammatory, helping to generate collagen and hyaluronic acid for improved skin health and aiding in the production of endothelial nitric oxide which helps to dilate blood . Learn about all the potential benefits of Pycnogenol and find out which ones are most supported by science. Children who took a pine bark extract supplement for one month had healthy antioxidant levels. Pycnogenol acts as a sustained-release formulation. Health Benefits of L-Arginine - WebMD Circulation and Jet Lag on Long Flights. SelfDecode is a personalized health report service, For example, Enzogenol is an extract from a pine that grows in California and Mexico (Pinus radiata) that may have cognitive-enhancing effects. Pycnogenol seems well-tolerated for use in adults for up to 6 months. Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). There have been a variety of health benefits linked to beta glucan, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides. DOI: Scheff SW, et al. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. Pycnogenol: Uses and Risks - WebMD But what makes this miracle ingredient so amazing? Add to Cart. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. (1, 2). Pycnogenol: Health Benefits, Uses, Doses, Safety Information - WebMD Pycnogenol-treated patients had significant improvement in symptoms as well as a reduction in leg swelling as compared to those not receiving treatment. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. are clickable links to these studies. Pycnogenol is the registered trademark name for a French formula. Ginkgo biloba has been widely cultivated across the globe for a variety of uses, most of which are medicinal. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. Can you get pycnogenol naturally from foods? High-dose Pycnogenol (360 mg/day) for 4 weeks had the same LDL-lowering benefits in another study of 40 people [32, 56]. First and foremost, start eating an anti-inflammatory Local Raw Honey (Bee Pollen) Considering how good it tastes, having some raw honey Apple Cider Vinegar (ACV) You can now find high-quality apple cider vinegar in . It can also stabilize mast cells, which release histamine and trigger allergic reactions. We don't yet know what the best dose to use is, but studies have used two 50 mg Pycnogenol capsules per day. Pycnogenol may stimulate the immune system. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. Treatment of ADHD with French maritime pine bark extract, Pycnogenol [Abstract]. Prenatal nutrition can be confusing. Your email address will not be published. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for treating conventional diabetes may be beneficial. Some research suggests that procyanidins may have antioxidant and anti-inflammatory activity. 7. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. Taking pine bark extract also increases the blood . Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. Vertigo. Today, I want to share with you my secrets to reduce sugar Top 7 Benefits of Green Tea: The No. They also had normalized fasting glucose levels and blood pressure, which can also reduce a persons risk of heart problems. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. So it may not be safe for people with immune disorders, such as: It's not known if pycnogenol is safe for children or for women who are pregnant or breastfeeding. Pycnogenol effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women [Abstract]. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Dr. Steven Lamm did a great job at explaining the new benefits of pycnogenol. Lower the risk of Alzheimer's disease. Regardless, a natural option is available and far worth the wait. (2015). ", Journal of Medicinal Food: "Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine Bark, Pycnogenol. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. The Benefits of DIM - Fort Wayne Physical Medicine Vinpocetine is a well-known substance in the health-hacking community with a variety of claimed health benefits. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. Pine bark extract may be the perfect treatment since its an antioxidant dynamo. No side effects were noted, unlike its synthetic counterpart. Here are the many health benefits believed to be possible with Pycnogenol: Now lets dive into the first condition it could help treat. Pycnogenol French maritime pine bark extract acts as a potent blend of antioxidants, it is a natural anti-inflammatory, stimulates generation of collagen and hyaluronic acid and help with natural dilation of blood vessels by supporting production of nitric oxide. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. It also slightly decreased blood pressure and increased testosterone [67]. In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. Both supplements are antioxidants, which have been shown to help with blood flow and erectile function. Next, the doctors discuss the link between salt and hypertension, and Dr. Steve gives his insight on drinking red wine for a healthy heart. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. Headaches. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. In contrast, bleeding still occurred in the control group [61]. Dr. Eric L. Zielinski is a sought-after natural . We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. It also provides powerful antioxidant protection and helps inhibit inflammatory factors to support. However, it's always a good idea to start with a low dose so you can monitor how your body responds. (2006). Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation. 1) Encourages Healthy Blood Pressure. The crew fell extremely ill from scurvy, an extreme lack of vitamin C. Cartiers crew crossed paths with a Quebec Indian who encouraged them to drink a tea made from pine bark and needles. Another group of men who took just l-arginine didnt improve [66]. It can then lead to heart problems like stroke or heart attack. Considering that about 1 of 3 adults in the U . Pycnogenol; Pycnogenol. Possess Anti-Inflammatory Action. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . $31.99. It does this by improving the time it takes the body to reach a fatigued state through increased serum NAD+ levels. New Study: Daily Use of Pycnogenol Provides Benefits for Men Managing New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. The antibacterial activity was assessed indicating that the essential oil of pine bark, specifically the proanthocyanidins, were effective against P. aeruginosa, significantly inhibiting its growth. Research indicates that Pycnogenol provides an increase in survival performance of train athletes. Disease of the retina in the eye. - Please read carefully and implement principles included in the Health Recovery Plan. Various brands of pycnogenol are available. But what are its health benefits? Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. Lutein Benefits, Uses, Foods, Side Effects and More - Dr. Axe Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. Importantly, all studies found that Pycnogenol has to be taken at least 5 weeks before the allergy season in order to see potential benefits, with the best results in those who take it 7-8 weeks ahead. Pycnogenol (150 mg/day) reduced LDL and increased HDL cholesterol in a trial of 25 healthy people after 6 weeks [55]. Regulations set manufacturing standards for supplements, but that does not guarantee that they are safe or effective. It has been studied for its effects on everything from mental function to treating high blood pressure. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Pycnogenol Why Should Men Like You Care? - ManTripping Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. Benefits of Pycnogenol - Healthy Directions returned. If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. Pycnogenol is the registered trademark brand name of French maritime pine bark extract. Normalization of cardiovascular risk factors in peri-menopausal women with Pycnogenol [Abstract]. Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. Jonathan Ritter, PharmD, PhD (Pharmacology), Small molecule antioxidants (phenolic acids, catechin, and taxifolin) are quickly absorbed and begin to act in the body within 30 min, The remaining more complex antioxidants (long chains of procyanidins) reach the gut, where your, The microbiome-produced active compounds appear in blood 6 h later and remain for at least 14 h, Pycnogenol is standardized to contain 70 5% procyanidins, which should be on the label, Pycnogenol standardization doesnt determine other major active compounds, which can vary. Along with the rest of the crew, he developed symptoms of vitamin-C deficiency. Research into Pycnogenol has revealed some promising results in over 30 health conditions. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. Chemistry. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37].

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